6stringnut, et al,
Ah, yes! The probability theory.
(COMMENT)
The vastness of space, the probability, and the chemistry...
Based on what we know about the universe, the probability is that there is intelligent life, or has been intelligent life, somewhere else in the universe.
But the probabilities also tell us that it is unlikely that we will ever make contact (interaction) with them for the very reason that the vastness is so great. The probabilities are greater that we might "detect" the presence of intelligence life, but against amazing high odds. Still more probable, yet high odds, is that some evidence of a lower form of life may be discovered.
Most Respectfully,
R