Alcohol or weed. Not alcohol and weed. What a frightening story.
Mixing things tend to be really bad. My drug of choice is alcohol, and I learned very early to drink only one thing, and stick with it all evening. If nothing else, it reduces the chance of a hangover. So if I start the evening with scotch, it's scotch for the night. If I start with white wine, that's it for the night. Well, that's what I did back when I drank.
Now that I'm old, it takes very little to affect me, and I tend to just go to sleep, so it isn't much fun either. I think I used up my lifetime allotment of alcohol when I was 43 or so.