If a cabinet post remains unfilled?

Supposn said:

If a cabinet post remains unfilled?

What effectively would be an administration's problems if the senate refused to confirm all of the president's nominations for one or more cabinet posts and the offices remain unfilled?
Respectfully, Supposn

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The remedy the U.S. Constitution provides is a "recess appointment" which can be made to fill a vacancy in an office that would otherwise require U.S. Senate approval (even a U.S. Supreme Court justice) for the remainder of the Congressional session.

But recess appointments can only be made while the U.S. Senate is not in session, something that was historically common, but is now rare.

https://politics.stackexchange.com/...binet-department-position-unfilled-for-longer